Experimental models – In vivo pain models of mice and rats
- Acute chemonociception: examination of nocifensive behaviours in the:
- PMA (phorbol-myristil-acetate) and formalin (somatic) tests
- Acetic acid-, magnesium-sulphate and phenylquinone-induced writhing test (visceral)
- Thermonociceptive tests:
- Heat threshold measurements, RTX-, OLDA-, capsaicin-induced heat allodynia tests
- Mechanonocipetion tests: measurement of pressure and touch sensitivity thresholds
- Migraine and chronic neuropathy: Mouse/rat models of traumatic mononeuropathy, diabetic polyneuropathy, toxic polyneuropathy, and bone metastasis-induced neuropathic pain.
Models of acute and chronic stress
- Tail suspension and forced swim tests
- Chronic restraint stress
- Chronic variable stress
