Experimental models – In vitro models
- Perfusion system: Measurement of the release of sensory neuropeptides (substance P, CGRP and somatostatin and PACAP) from isolated organs, especially rat trachea with specific and sensitive radioimmunoassay techniques developed in our laboratory
- Murine and rat peritoneal macrophage cultures: Measurement of cytokine (especially IL-1-beta and TNF-alpha) production in response to LPS and PMA stimulation
- Primary culture of trigeminal neurones, astrocytes, peritoneal macrophages and receptor (TRPV1, TRPA1, sst1-5) expressing cell lines made in our laboratories: examination of ligand-receptor binding and receptor activation